Reporting to – Chief Executive Officer
Key relationships – Strong, productive relationships across the organisation and externally are essential for success.
Salary – The salary is subject to cabinet approval but will be commensurate with the seniority of the role.

Role Purpose


This is a generational opportunity to lead the next chapter in Genomics England’s global scientific and clinical impact as Chief Scientist. Building on the success of the “moonshot” 100,000 Genomes Project, Genomics England is now bringing the benefits of genomic medicine to everyone in England, the UK and beyond, in close partnership with the NHS. We are seeking an experienced scientific leader, with a track record of successfully leading diverse, high performing teams and collaborative research partnerships. As a key member of a dynamic and relatively new executive leadership team (ELT) and member of the Board, the Chief Scientist will shape Genomics England’s emerging strategy, and scale its ground-breaking work.

The ideal candidate will be attracted by the numerous opportunities at Genomics England for translational research, and by working closely with a wide range of colleagues to turn science into healthcare and positive patient outcomes using technology. You can find more information on the real impact of our work on patients via Additional Resources on our Strategy page. They will be an advocate for Genomics England with relevant senior stakeholders in the genomic landscape across UK and international research, academia, and pharma. They will be as comfortable taking a meeting with the Secretary of State as sitting with a group of research participants to understand their priorities. They will be familiar with relevant technologies and the roles of the private, academic and public sectors as partners. Through their expertise, in partnership across the Genomics England ecosystem, they will drive and promote new data, technologies and innovation.

Reporting to and working in close partnership with the CEO, the Chief Scientist will lead a multi-disciplinary team in contributing to, and executing against, the Genomics England strategy to deliver the world’s best genomic medicine to the people of the United Kingdom and to federate this knowledge, ensuring the UK remains a recognised global leader as a “science superpower”.

Key Accountabilities



This person will:

  • build and lead a team to develop, deliver and scale scientific assets to enable the genomics community (e.g. relevant aggregate datasets, new bioinformatics/machine learning approaches to genome analysis);
  • be a strategic thinker, responsible for driving decision-making across scientific areas of focus to achieve Genomics England’s goals;
  • lead and manage a team of deep domain specialists and manage the science directorate in Genomics England, in an inclusive, tech-enabled way;
  • bring expertise in a relevant scientific field and the ability to play confidently across related fields such as the genomics and multi-omics of rare disease, cancer and infectious disease; sequencing technology advances; genome analysis and bioinformatics; target discovery & development; pharmacogenomics; and Polygenic Risk Scores;
  • be excited to build data assets, infrastructure.


  • lead the science and data strategy development and delivery process; scientific analysis strategy; and research publication strategy;
  • lead decision-making on scientific areas of focus driven by Genomics England’s goals and on domain strategy (e.g. disease areas, functional genomics, pharmacogenomics, newborns, cancer diagnostics);
  • assess possible areas where the organisation can proactively embed government strategy and organisational goals;
  • bring a researcher perspective to the organisation’s Research Ecosystem;
  • work closely with clinical colleagues and partners to provide scientific oversight of our healthcare service.

Advocacy and Stakeholder Management

This person will:
  • represent the organisation externally on science topics at research institutes; at industry events; parliamentary questions; and with SAGE, Ministers and Government more broadly;
  • guide the genomics user community in accessing Genomics England data assets and contributing to scientific knowledge;
  • lead Genomics England’s scientific activities and contributions with a focus on enabling the research of others, to enhance not only the organisation’s reputation, but the UK’s reputation at the forefront of genomic research and healthcare;
  • own the Genomics England research protocol, ethical agenda, and interactions with various Research Ethics Committees;
  • lead and manage (with the Ecosystem Partnerships team) Genomic England’s scientific stakeholders, based on existing and new networks of deep and instrumental relationships with a focus on building trust across scientific communities including:
  • Science Advisory Committee;
  • Access Review Committee;
  • Ethics Advisory Committee;
  • Participant Panel;
  • Scientific Elements of Ecosystem partnerships;
  • Genomic England Clinical Interpretation Partnership;
  • Science contacts at major pharma (e.g. Life Sciences Council);
  • Major funders e.g., Wellcome, UKRI (inc. Innovate UK, MRC), CRUK;
  • Elite journals e.g., Nature, Science, NEJM, STAT.